Association of lipoprotein indices with 3-month functional outcome after ischemic stroke: a retrospective cohort study
Lipid-related parameters have been linked to vascular risk, yet their association with post-stroke functional recovery remains uncertain. We aimed to examine whether lipoprotein imbalance is associated with 3-month funct
\n\nIn a retrospective cohort study, researchers investigated the relationship between lipid-related parameters and functional outcome after ischemic stroke. The study included 748 patients with acute ischemic stroke, who were assessed for poor functional outcome at 3 months. Fourteen lipid-related parameters were analyzed, including LDL-related measures.\n\nAccording to the study, each unit increase in lbLDL-C/HDL-C was independently associated with poor functional outcome.\n\nThe researchers used multivariable logistic regression, generalized additive models, two-piecewise regression, and subgroup analyses to examine the association between lipid-related parameters and functional outcome.\n\nThe study found that lipid-related measures were associated with poor functional outcome, suggesting that lipoprotein imbalance may be an important factor in post-stroke recovery.\n\nHowever, the study also noted that the association between lipid-related parameters and functional outcome was complex and influenced by multiple factors, including age, sex, and comorbid conditions.\n\nOverall, the study provides new insights into the relationship between lipid-related parameters and functional outcome after ischemic stroke, highlighting the importance of lipid management in post-stroke care.\n\nThis study was published in [Journal Name], and its findings have implications for the management of patients with ischemic stroke and the development of new therapeutic strategies to improve functional outcomes.