What is TB-500?
TB-500 is the research name commonly used for a synthetic fragment of thymosin beta-4, an actin-sequestering peptide involved in cell migration and cytoskeletal remodeling. All catalog material is for laboratory research use only.
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TB-500
Thymosin β4 fragment · actin-binding research
Injectable
2–5 mg
2× weekly loading
PRECLINICAL
Overview
Key Benefits
Cell-migration and wound-closure assays, soft-tissue models, often stacked in catalogs with BPC-157.
Mechanism of Action
Thymosin β4 binds G-actin and is studied for endothelial migration, wound-closure assays, and cardiac-repair models. TB-500 preparations are sold as research fragments, not as licensed thymosin drugs.
Molecular Information
- Weight
- Combined — see CoA
- Length
- 7 amino acids (17–23 fragment)
- Type
- Thymosin β4 fragment
- Formula
- —
Amino Acid Sequence
Blend: BPC-157 + TB-4 fragment (17–23); see monographs for each chain.
Research directions
Repair biology Preclinical
- Migration and angiogenesis readouts
Pharmacokinetics
Peak hours (parenteral models)
Half-life hours (fragment-dependent)
Cleared within a day in typical models
Literature PK is sparse and fragment-specific.
Literature
- Thymosin β4 in tissue repair — 2012 · Review. Actin-binding peptide biology.