peptides-pro
Journal
2,940 articles
- Stigmasterol ameliorates obesity-associated insulin resistance by activating the PPARγ pathway and alleviating oxidative stress ObjectiveThis study aimed to investigate the effects of stigmasterol on obesity-related insulin resistance and...
- Adipokine, endocrine, and fibrinolysis-related alterations across abdominal obesity and metabolic syndrome phenotypes in young adults BackgroundAbdominal obesity in young adults may reflect a biologically active metabolic phenotype, even before...
- Real-world semaglutide in obesity cohort: effectiveness, safety and persistence across sex, BMI, and prior GLP-1RA treatment Semaglutide has shown significant efficacy in several clinical trials for the treatment of obesity. However, r...
-
Editorial: Sex steroid metabolism and obesity: insights from animal studies
Obesity rates are rapidly increasing globally, with marked differences in fat distribution often reported betw...
- Serum SH2B1 and SULT1A2 in relation to adiposity and early weight-loss response: a hypothesis-generating study BackgroundIndividual responses to weight loss interventions are highly heterogeneous. This study aimed to expl...
- Research progress on the relationship and mechanisms of obesity, gut microbiota, and natural medicines Obesity has become a major global public health challenge, affecting more than 1.5 billion people worldwide an...
- Untitled ObjectiveTo evaluate the predictive value of endometrial and uterine artery blood flow parameters, combined wi...
- Untitled BackgroundLaparoscopic sleeve gastrectomy is an effective metabolic surgery; however, some patients experience...
- CD8+ T cell heterogeneity and function in lupus nephritis: a focused review Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus marked by immune complex deposi...
- From mechanical adaptation to innate immune reprogramming in osteoarthritis: a load-immunity framework Osteoarthritis (OA) is a whole-joint disease in which mechanical exposure and low-grade sterile inflammation i...
- Microenvironment-defined priority pathways shape ICD-driven abscopal responses While radiotherapy excels at local tumor control, it seldom orchestrates durable systemic immunity in the cont...
- Mitochondrial DNA in systemic lupus erythematosus: pathogenic mechanisms, clinical biomarkers, and precision therapeutic strategies Mitochondrial DNA (mtDNA) is increasingly recognized as an active driver of immune dysregulation in systemic l...
- Daily HIV pre-exposure prophylaxis enhances monocyte activation and reprogrammes immune cell metabolism IntroductionPre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) is highly effective for HIV...
- Copper homeostasis and organelle-dependent mechanisms in bone metabolism: implications for osteoporosis therapy BackgroundOsteoporosis is a prevalent metabolic bone disorder driven by an imbalance between osteoblast-mediat...
- THAP7-AS1 sponges miR-4286 to upregulate PFKFB2, accelerating aerobic glycolysis and aggravating liver cancer progression BackgroundLiver cancer ranks among the most prevalent and deadliest malignancies worldwide. As one of the larg...
- Hypoxia-driven crosstalk among cardiac fibroblasts, macrophages, and endothelial cells in cardiac fibrosis Cardiac fibrosis, a hallmark of adverse remodeling following myocardial infarction (MI), markedly contributes...
- Biliary atresia-related liver fibrosis Biliary atresia (BA) is a devastating cholestatic disease of infancy characterized by progressive fibro-oblite...
- Mitochondrial regulation of cellular senescence heterogeneity Cellular senescence is a stable cell-cycle arrest program accompanied by extensive metabolic remodeling and ac...