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Cagrilintide

Long-acting amylin analogue

Injectable 2.4mg, Once weekly, same day each week Once weekly CLINICAL PROGRAMS

Overview

What is Cagrilintide?

Cagrilintide is a long-acting amylin analogue developed for metabolic research and clinical programs, often discussed alongside GLP-1 agonists. It is not a licensed monotherapy in most markets. All catalog material is for laboratory research use only.

Key Benefits

Amylin receptor agonist, Satiety and gastric-emptying models, Combination literature with incretins

Mechanism of Action

Amylin receptors in the area postrema and hypothalamus contribute to satiety and gastric-emptying control. Acylated analogues extend half-life versus native amylin.

Molecular Information

Weight
~4900 g/mol (approx., variant-dependent)
Length
9 amino acids
Type
Cagrilintide
Formula
Amino Acid Sequence Long-acting amylin analog (acylated); primary structure on certificate.

Research directions

Obesity development Clinical programs

  • Standalone and incretin combination studies

Pharmacokinetics

Peak days (long-acting analogue)
Half-life several days (clinical-development reports)
Cleared weeks-scale

Development PK, not a protocol.

Literature

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