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Melanotan II

Non-selective melanocortin agonist

Injectable 1mg, Once daily Once daily PRECLINICAL / UNOFFICIAL USE LITERATURE

Overview

What is Melanotan II?

Melanotan II is a cyclic lactam analogue of α-MSH. It tans in research and anecdotal settings via MC1R and has central MC3/4 effects. It is not an approved tanning drug in major markets. All catalog material is for laboratory research use only.

Key Benefits

α-MSH analogue, MC1R pigmentation, Central melanocortin effects

Mechanism of Action

Broad melanocortin agonism explains pigmentation, appetite, and sexual-function signals in the literature. Off-target nausea is commonly noted in reports.

Molecular Information

Weight
1024.2 g/mol
Length
10 amino acids
Type
Melanotan II (Melanocortin Receptor Agonist)
Formula
C50H69N9O9
Amino Acid Sequence Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-OH (lactam bridge)

Research directions

Pigmentation models Preclinical / unofficial use literature

  • Melanogenesis

Pharmacokinetics

Peak hours
Half-life hours–longer (depot-like in reports)
Cleared days-scale pigmentation effect ≠ plasma PK

Pigment kinetics outlast plasma peptide.

Literature

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