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Semax

ACTH(4-10) analogue · cognitive research

Nasal 6mcg, Once daily Once daily PRECLINICAL / REGIONAL

Overview

What is Semax?

Semax is a synthetic ACTH(4-10) analogue with a Pro-Gly-Pro C-terminus, studied for nootropic, neuroprotective, and BDNF-related effects. Licensed use exists in some jurisdictions; research vials are not those medicines. All catalog material is for laboratory research use only.

Key Benefits

ACTH fragment analogue, BDNF-related papers, Stroke and cognitive models

Mechanism of Action

Papers describe effects on BDNF/trkB, copper-zinc SOD, and monoamines. Intranasal designs dominate the original literature.

Molecular Information

Weight
813.9 g/mol
Length
7 amino acids
Type
Methionyl-Glutamyl-Histidyl-Phenylalanyl-Prolyl-Glycyl-Proline
Formula
C37H51N9O10S
Amino Acid Sequence Met-Glu-His-Phe-Pro-Gly-Pro

Research directions

Neuroprotection Preclinical / regional

  • Ischemia and cognitive assays

Pharmacokinetics

Peak minutes–hour (intranasal models)
Half-life short
Cleared hours

Regional clinical + rodent PK.

Literature

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