The Elusive Role of NAD+: Unveiling the Mysteries of Cellular Energy Metabolism
NAD+ (Nicotinamide adenine dinucleotide) is a crucial coenzyme in cellular energy metabolism, yet its precise role remains shrouded in mystery. This review aims to provide an overview of the current understanding of NAD+
NAD+ is a vital molecule that plays a central role in maintaining cellular homeostasis. As a coenzyme, it participates in numerous redox reactions, facilitating the transfer of electrons in various biochemical pathways. The discovery of NAD+-dependent enzymes has expanded our understanding of cellular metabolism, but the exact mechanisms by which NAD+ regulates these processes remain poorly understood. Recent advances in NAD+ biosynthesis and the development of NAD+-boosting therapies have sparked renewed interest in the molecule's role in human health and disease. This review will provide an overview of the current state of knowledge on NAD+, highlighting its involvement in energy metabolism, DNA repair, and epigenetic regulation, as well as its potential as a therapeutic target for various diseases.