peptides-pro
Journal
2,940 articles
- Design, one-pot green synthesis, computational studies, and biological evaluation of novel pyran-pyridine hybrids for targeting MCF-7 breast cancer cell line This study reports a catalyst-free, one-pot synthesis of novel pyran-pyridine hybrids (4a–j). The target compo...
- Structural determinants for FAT10 activation and transfer from UBA6 to E2 enzymes Cryo-EM captures FAT10 activation and transfer from UBA6 to E2 UBE2Z, revealing FAT10 monopolises UBA6. Effici...
- Decay of the Lef1-Srsf3-microRNA axis impairs DNA damage response and underlies stem cell aging Stem cell (SC) aging is implicated in tissue dysfunction and organismal aging. However, the molecular basis of...
- Cysteine preconditioning improves post-freeze-thaw proliferative capacity of human synovial mesenchymal stem cells Synovial mesenchymal stem cells (MSCs) are promising for cartilage regeneration, but freeze–thaw injury can re...
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How the discovery of mammalian regeneration shapes translational efforts
This Journal Club highlights the landmark study that provided the first evidence of regeneration in mammals, d...
- TMEM189/PEDS1 deficiency aggravates MASH progression by promoting FASN-mediated macrophage activation Transmembrane protein 189 (TMEM189), also known as plasmanylethanolamine desaturase 1 (PEDS1), is involved in...
- Peripheral autonomic dysfunction and vascular mechanics in non-diabetic hypertensive patients: a pilot study using electrochemical skin conductance The clinical significance of peripheral autonomic dysfunction in assessing cardiovascular risk in non-diabetic...
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Formylpeptide receptor activation attenuates renovascular remodeling in neurogenic hypertension
Formylpeptide receptor agonism with Compound 17b lowers blood pressure, restores vascular function, and revers...
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Obesity-associated unfolded protein response, oxidative stress, and NRF2 signaling
Obesity has become a major global health problem. It is characterized by increased body fat storage and is ass...
- Handgrip strength is not independently associated with steatosis in people with MASLD Reduced handgrip strength (HGS) is considered a surrogate marker of whole-body muscle strength and has been as...
- Untitled Open-weight large language models (LLMs) can be deployed locally at low cost, making them attractive for patie...
- Leave no one behind: optimizing kidney protection in type 1 diabetes Despite unprecedented advances in the treatment of non-diabetic chronic kidney disease (CKD) and CKD in type 2...
- Triglyceride–high-density lipoprotein cholesterol–glucose–body mass index predicts 28-day all-cause mortality in critically ill patients with heart failure The prognostic value of the triglyceride–high-density lipoprotein cholesterol–glucose–body mass index (TyHGB)...
- Leadership for the postdoctoral to independent investigator transition The transition from postdoctoral researcher to independent investigator is marked by complex decision-making a...
- Transcriptome profile of peripancreatic adipose tissue in pancreatitis Chronic pancreatitis (CP) is a progressive inflammatory disease marked by extensive fibrosis that ultimately i...
- Leave no one behind: optimizing kidney protection in type 1 diabetes Despite unprecedented advances in the treatment of non-diabetic chronic kidney disease (CKD) and CKD in type 2...
- In silico design of a novel therapeutic multi-epitope vaccine against NSCLC: a reverse vaccinology approach Non-small cell lung cancer (NSCLC) remains one of the leading causes of cancer-related deaths worldwide, highl...
- Computational profiling and rational design of peptide inhibitors targeting trypsin in Helicoverpa armigera (Hübner): A structure-based approach This study computationally evaluates the inhibitory potential of peptides derived from protease pro-regions an...