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Ipamorelin

Selective GHSR / GHRP analogue

Injectable 200–300 mcg 1–3× daily CLASSIC PHARMACOLOGY

Overview

What is Ipamorelin?

Ipamorelin is a pentapeptide growth-hormone secretagogue with relatively selective GHSR (ghrelin receptor) activity and less ACTH/cortisol signal than older GHRPs in classic papers. All catalog material is for laboratory research use only.

Key Benefits

Pulsatile GH release models, selectivity versus hexarelin/GHRP-6, commonly catalog-paired with GHRH analogues such as CJC-1295.

Mechanism of Action

GHSR activation on pituitary somatotrophs releases GH in pulses. Selectivity versus hexarelin/GHRP-6 is a key reason it appears in research catalogs.

Quick Start Guide

Typical Dose 200–300 mcg
How Often 1–3× daily
Where to Inject Abdomen or thigh
Injection Timing Often evening / around fasting in research-community schedules
Effects Timeline GH pulse in under an hour; composition research over weeks
Storage Lyophilized refrigerate; reconstituted ~30 days cold
Cycle Length 8–12 weeks
Break Between 4 weeks

Molecular Information

Weight: 711.9 g/mol
Length: 5 amino acids
Type: Selective GHSR / GHRP analogue
Formula: C38H49N9O5

Amino Acid Sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2

Research directions

Somatotropic axis Classic pharmacology

Selective GH release assays

Pharmacokinetics

Peak ~30–60 min GH pulse (research PK)

Half-life ~2 h (reported)

Cleared hours

GH pulse timing is not a dosing guide.

Literature

Raun et al., ipamorelin — 1998 · Pharmacology. Selective GH secretagogue.

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Related: CJC-1295, GHRP-6, Hexarelin, Sermorelin

Encyclopedia snapshot for laboratory research context. Not medical advice and not a personal protocol.