What is Sermorelin?
Sermorelin is GHRH(1-29) amide, the shortest fully active GHRH fragment historically used in diagnostic GH-stimulation testing. Research vials are not diagnostic kits. All catalog material is for laboratory research use only.
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Sermorelin
GHRH(1-29) amide
Injectable
3mcg, Once daily
Once daily
HISTORICAL CLINICAL
Overview
Key Benefits
Native-length GHRH fragment, Diagnostic-history molecule, Short GH pulse
Mechanism of Action
It binds the GHRH receptor with a short half-life, producing a brief GH pulse — useful historically to probe pituitary reserve.
Molecular Information
- Weight
- 3357.9 g/mol
- Length
- 29 amino acids
- Type
- Sermorelin (Growth Hormone-Releasing Hormone 1-29)
- Formula
- C149H246N44O42S
Amino Acid Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Asn-Arg-NH2
Research directions
Pituitary testing history Historical clinical
- GH stimulation tests
Pharmacokinetics
Peak ~20–30 min GH
Half-life ~10–20 min
Cleared rapid
Very short peptide.
Literature
- Sermorelin reviews — 1999 · Review. GHRH(1-29) as a diagnostic secretagogue.