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Thymosin Alpha-1

28-aa thymic peptide (Tα1)

Injectable 1.6mg, biweekly biweekly CLINICAL (LICENSED DRUG) + RESEARCH

Overview

What is Thymosin Alpha-1?

Thymosin alpha-1 is a 28-residue acetylated peptide from the thymus. A licensed product (e.g. Zadaxin in some markets) exists as an immune modulator. Research vials are not that medicine. All catalog material is for laboratory research use only.

Key Benefits

Defined 28-mer, Immune-modulation literature, Licensed product exists separately

Mechanism of Action

Tα1 is studied for T-cell maturation, TLR signaling in antigen-presenting cells, and adjunct immune-research settings.

Molecular Information

Weight
3108.3 g/mol
Length
23 amino acids
Type
Thymosin Alpha-1 (Thymalfasin)
Formula
C129H215N33O55
Amino Acid Sequence Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Gln-Lys-Glu-Asp-Val-Glu

Research directions

Immune modulation Clinical (licensed drug) + research

  • Vaccine adjuvant and infection-adjunct papers

Pharmacokinetics

Peak hours SC (licensed PK)
Half-life ~2 h
Cleared hours

Licensed-product PK.

Literature

  • Tα1 reviews — 2010 · Review. Thymosin alpha-1 immunology.
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