peptides-pro
Journal
2,940 articles
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Carbon source–driven metabolic and regulatory remodeling defines phenomic states in Lipomyces starkeyi
Lipomyces is a genus of oleaginous yeasts with potential for contributing to reliable biomanufacturing supply...
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Designing non-natural RNA-guided nucleases
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the...
- Structural molecule–associated protein changes in SUMO1-deficient mice are associated with attenuated age-related anxiety-like behavior SUMO1 is essential for normal neural function, yet its role in age-related behavioral changes remains unclear....
- Nuclear aging in polyglutamine-induced neurodegeneration Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder caused by a CAG over-repetiti...
- Untitled Highland soil environments represent ecologically dynamic habitats that may harbor metabolically versatile and...
- Untitled Adipose-derived mesenchymal stromal cells (ADMSCs) display heterogeneous metabolic responses that may underlie...
- Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate (S1P) is a potent lipid signaling molecule. Here, the authors determine the cryo-EM st...
- TDP-43 controls RNA structure through high affinity lattice interactions TDP-43 is an essential RNA-binding protein. Here, the authors show how it binds single-stranded poly(UG) RNA t...
- IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participants Although low-dose IL-2 therapy has shown promise in treating autoimmune and inflammatory conditions by support...
- Alginate attenuates reactive microglia in vivo Alginate is a marine polysaccharide commonly used in the form of hydrogel in different biomedical applications...
- Concomitant ablation of SOS1 and SOS2 triggers a lethal phenotype involving compromised intestinal integrity and widespread septicemia The RAS guanine nucleotide exchange factors Son of Sevenless 1 and 2 (SOS1 and SOS2) are key regulators of RAS...
- IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participants Although low-dose IL-2 therapy has shown promise in treating autoimmune and inflammatory conditions by support...
- IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participants Although low-dose IL-2 therapy has shown promise in treating autoimmune and inflammatory conditions by support...
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Adolescent weight gain trajectories and their associations with biological aging: a genetically informed study
High body mass index (BMI) in adolescence is associated with accelerated biological aging, which might predict...
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Cathepsin D-driven IL2RG–JAK2 signal hijacking disrupts hepatic insulin action: mechanism-grounded proof that targeting cathepsin D prevents prediabetes
Hepatic insulin resistance (HIR), an early feature of prediabetic, plays a pivotal role in disrupting glucose...
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Glucose-responsive probiotics for glycaemic modulation in mice and monkeys
Engineered probiotics equipped with a synthetic glucose-responsive circuit transiently colonize the gut and se...
- Fixational saccades and drift parameters are altered in poorly controlled type 2 diabetes mellitus: a pilot study Type 2 diabetes mellitus (T2DM) is a prevalent metabolic condition associated with neuronal and vascular compl...
- The progressive impact of obesity severity on systemic inflammation and atherogenic dyslipidemia: a multicenter cohort study Obesity-associated cardiometabolic risk involves a complex interplay of systemic inflammation and atherogenic...