peptides-pro
Journal
2,940 articles
- Bone Marrow Adipoq-Lineage Cells: Identities, Functions, and Mechanisms Bone marrow Adipoq-lineage cells refer to all cells that have ever expressed Adipoq (Adiponectin) and their pr...
- Differential regulation of neutrophil degranulation by p38 MAPK and mitochondrial ROS during Mycobacterium lep Erythema Nodosum Leprosum (ENL) is an inflammatory complication of leprosy associated with peripheral nerve da...
- Overcoming Translational Barriers for Natural Bioactive Peptides Bioactive peptides from natural sources exhibit potent antimicrobial, antihypertensive, antioxidant, and antic...
- Effects of herbal medicines and their phytoconstituents on vagus nerve stimulation: a systematic review of in The vagus nerve regulates autonomic, inflammatory, metabolic, and neurobehavioral functions. Although invasive...
- Absorption, distribution, metabolism, and excretion of [14C]SH-1028, a third-generation EGFR-TKI, in rats and SH-1028 is an irreversible third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-T...
- Gut Microbiota and the Gut–Liver Axis in MASLD: Mechanisms, Immune Regulation, and Therapeutic Opportunities Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the most common chronic liver disea...
- A novel redox signalling axis mediates nicotine-induced podocyte injury Nicotine has been shown to induce Nlrp3 inflammasome activation, thereby contributing to podocyte injury. The...
- Role of PCSK9 in breast cancer: a systematic review of its mechanistic pathways and clinical relevance IntroductionBreast cancer is a heterogeneous disease in which accurate classification based on biomarker expre...
- Untitled Mitochondria play a central role in cellular metabolism, not only by generating ATP through oxidative phosphor...
- Efficient experimental characterization of the GPCRome via deep receptor scanning Here, the authors introduce deep receptor scanning methodology to enable characterization of 940 human GPCRs i...
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Alignment with experimental data improves protein generative modeling
Direct preference optimization (DPO) aligns a pretrained protein language model with experimental stability da...
- Deciphering the evolutionary origin of the enantioselectivity of short-chain dehydrogenases from plants toward 1-borneol Enzyme engineering has enabled optimization of enzymes for biotechnological processes, however, less is known...
- Anti-inflammatory and anti-mitotic properties of donepezil in primary keratinocytes and T cells support therapeutic potential for inflammatory skin diseases The non-neuronal acetylcholine system in skin produces anti-inflammatory effects beneficial for conditions lik...
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New Insights into Binding of G-segment DNA to the Active Site of Escherichia coli Topoisomerase III
Escherichia coli topoisomerase III (EcTopo3) is a type IA topoisomerase that binds single-stranded DNA (ssDNA)...
- TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation This study presents togoPhosTAC, a biologic platform that directs engineered phosphatases to target proteins f...
- TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation This study presents togoPhosTAC, a biologic platform that directs engineered phosphatases to target proteins f...
- Evolutionary conservation analysis reveals a primordial function of STING as a regulator of lipid metabolism via FADS2 STING is a well-known activator of type I interferon (IFN-I) responses. However, it is debated whether STING h...
- TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation This study presents togoPhosTAC, a biologic platform that directs engineered phosphatases to target proteins f...